Paper ID | MLR-APPL-BSIP.9 | ||
Paper Title | ADVANCED DEEP NETWORK WITH ATTENTION AND GENETIC-DRIVEN REINFORCEMENT LEARNING LAYER FOR AN EFFICIENT CANCER TREATMENT OUTCOME PREDICTION | ||
Authors | Francesco Rundo, STMicroelectronics, Italy; Giuseppe Luigi Banna, Queen Alexandra Hospital, United Kingdom; Francesca Trenta, Sebastiano Battiato, University of Catania, Italy | ||
Session | MLR-APPL-BSIP: Machine learning for biomedical signal and image processing | ||
Location | Area C | ||
Session Time: | Wednesday, 22 September, 08:00 - 09:30 | ||
Presentation Time: | Wednesday, 22 September, 08:00 - 09:30 | ||
Presentation | Poster | ||
Topic | Applications of Machine Learning: Machine learning for biomedical signal and image processing | ||
IEEE Xplore Open Preview | Click here to view in IEEE Xplore | ||
Abstract | In the last few years, medical researchers have investigated promising approaches for cancer treatment, leading to a major interest in the immunotherapeutic approach. The target of immunotherapy is to boost a subject's immune system in order to fight cancer. However, scientific studies confirmed that not all patients have a positive response to immunotherapy treatment. Medical research has long been engaged in the search for predictive immunotherapeutic-response bio-markers. Based on these considerations, we developed a non-invasive advanced pipeline with a downstream 3D deep classifier with attention and reinforcement learning for early prediction of patients responsive to immunotherapeutic treatment from related chest-abdomen CT-scan imaging. We have tested the proposed pipeline within a clinical trial that recruited patients with metastatic bladder cancer. Our experiment results achieved accuracy close to 93\%. |